Madonna publicly accused Harvey Weinstein of unwanted sexual advances, saying he 'crossed boundaries' when they worked together on her 1991 tour documentary. She has also spoken publicly about being raped at knifepoint during her early years. Although the specific incident of being raped was allegedly a separate incident, the seriousness of her remarks in the context of Weinstein is noteworthy.

Madonna's former husband Sean Penn was accused of physically abusing her, including reports of him tying her to a chair and beating her with a bat. Madonna spoke out in support of Penn, denying the abuse allegations. However, there are credible reports of Penn's abusive behavior, including a domestic assault charge.